SWT
Sweet Taste Preference
Class: I - Natural Selection
EPA Total Score: 31 /100
Striem, B. J., Pace, U., Zehavi, U., Naim, M., & Lancet, D. (1989). Sweet tastants stimulate adenylate cyclase coupled to GTP-binding protein in rat tongue membranes. Biochemical Journal, 260, 121-126.
Abstract: Sucrose and other saccharides, which produce an appealing taste in rats, were found to significantly stimulate the activity of adenylate cyclase in membranes derived from the anterior-dorsal region of rat tongue. In control membranes derived from either tongue muscle or tongue non-sensory epithelium, the effect of sugars on adenylate cyclase activity was either much smaller or absent. Sucrose enhanced adenylate cyclase activity in a dose-related manner, and this activation was dependent on the presence of guanine nucleotides, suggesting the involvement of a GTP-binding protein ('G-protein'). The activation of adenylate cyclase by various mono- and di-saccharides correlated with their electrophysiological potency. Among non-sugar sweeteners, sodium saccharin activated the enzyme, whereas aspartame and neohesperidin dihydrochalcone did not, in correlation with their sweet-taste effectiveness in the rat. Sucrose activation of the enzyme was partly inhibited by Cu2+ and Zn2+, in agreement with their effect on electrophysiological sweet-taste responses. Our results are consistent with a sweet-taste transduction mechanism involving specific receptors, a guanine-nucleotide-binding protein and the cyclic AMP-generating enzyme adenylate cyclase.
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10/100
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10/100
Submitted by DJGlass
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Supporting Evidence is evidence that suggests that this trait is an Evolved Psychological Adaptation (EPA) - i.e., that it has been shaped by natural selection to solve a particular adaptive problem.
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0/100
Submitted by DJGlass
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0/100
Submitted by DJGlass
No one has (yet) rated this source as containing any challenging Hunter-Gatherer evidence for this EPA.
Challenging Evidence is evidence that suggests that this trait is not an EPA - e.g., that it is a product of cultural learning or genetic drift, or maybe it does not exist at all. However over each line of evidence for a description.